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Why is Imitrex
prescribed?
Imitrex is prescribed for the treatment of a migraine attack with or without the presence of an aura (visual disturbances, usually sensations of halos or flickering lights, which precede an attack). The injectable form is also used to relieve cluster headache attacks. (Cluster headaches come on in waves, then disappear for long periods of time. They are limited to one side of the head, and occur mainly in men.)
DRUG INTERACTIONS: Sumatriptan is metabolized mainly by the liver and dosages may need to be reduced in patients with liver dysfunction. Sumatriptan can cause elevation of blood pressure and spasm of the coronary arteries of the heart. Sumatriptan should be avoided by patients with coronary artery disease (patients with angina pectoris and a history of heart attacks), and by patients with poorly controlled high blood pressure. It is administered with caution to patients with risk factors for coronary artery disease ( high blood pressure, diabetes, elevated blood cholesterol, obesity, cigarette smoking, and b family history of heart attacks). In some patients, the first dose of sumatriptan can be given in the physician's office to monitor any adverse heart events.
Sumatriptan should not be administered along with ergot type migraine medications, or with MAO inhibitors. Sumatriptan and ergotamine together can cause prolonged spasm of the blood vessels. Therefore, the use of these two medications should be separated by at least 24 hours. Safe use in children has not been established. Rarely, seizures after sumatriptan administration have been reported in patients with epilepsy.
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